Prince of Persia is set in a land rooted in ancient Persian mythology, with the Prince finding himself caught in an epic battle between the primal forces of light and darkness—the God of Light, Ormazd versus his brother Ahriman, the destructive God of Darkness. The Prince arrives just in time to witness the destruction of the legendary Tree of Life, an act which threatens to plunge the entire world into eternal darkness.

Manifested in the form of the Corruption, a dark substance that physically contaminates the land and the skies, the Prince must partner with Elika, a deadly companion, to heal the world from the evil Corruption.