Disease AnnihilatorG 75

Credit to Pandaman822 at TA for this solution. I take no credit for it, I am simply porting it here to disseminate the solution to as many sites as possible.

Start a game on the easiest difficulty - 2 epidemics only.

The Medic is strongly recommended based on their ability to clear cubes of cured diseases quickly . I would also recommend the Dispatcher to be able to move the Medic 4 additional moves each round when you are attempting to Eradicate diseases.

Recommended Characters: Researcher, Scientist, Medic (+Dispatcher if you're struggling to clear cubes)

Strategy
To have all 4 diseases Eradicated when you win the game, you have to either cure the 4th disease with no cubes at all on the board, or cure the 4th disease with the Medic occupying the same space as the last cubes on the board (they will get cleared once the disease is cured). Your goal throughout should be to eradicate diseases as you go, leaving yourself less work at the end where you might run out of time. As you get down to 2 or 1 diseases left to cure/eradicate, try and remember which cards are in the infection pile so you can locate your characters strategically for easy treating of cubes as they come on the board.

***My additions:
So in addition to Pandaman822's solution, I have a few extra thoughts. Yellow is the hardest disease to treat due to the limited routes of travel within Africa and South America. Eradicate yellow as quickly as possible, and if you find yourself in a game with a lot of yellow cities in the draw pile, seriously consider bailing on that game and starting a new one. The ideal game is one in which you can cure and eradicate yellow within the first round.

Hold on to One Quiet Night and Forecaster once you get them. It takes long enough to eradicate all 4 diseases that you'll basically run out the entire deck, so there's a 99% chance you WILL have them. Most ideal situation is to use those two cards to ensure that your board is completely clean by the time the scientist is at bat and can cure/eradicate the last disease in one fell swoop. Second most ideal situation is to use those cards to ensure that your medic is standing in the last (and only) infected city when the disease is cured so that the cubes are immediately cleared.